Detection of volatile compounds in urine using an electronic nose instrument
電子鼻檢測尿液中的揮發性化合物(VOCs)
Thowiba Mohamed Abdalla Sabeel UniversitiTeknologi Malaysia,UTM Skudai Johor – Malaysia thowibam
FauzanKhairiCheHarun UniversitiTeknologi Malaysia,UTM Skudai Johor, Malaysia fauzan@fke.utm.my
Stephan Enyinnaya Eluwa UniversitiTeknologi Malaysia,UTM Skudai Johor, Malaysia ellis772000
Solima Mohamed Abdalla Sabeel Khartoum University Khartoum, Sudan solima89
DOI:10.1109 / ICCEEE.2013.6633956
Abstract
Current clinical diagnostics are based on biochemical, physics and microbiological methods. The electronic nose system used to detect chemical components or VOCs in urine sample is meant to classify different urine components so as to be able to diagnose diseases and other elements accuray. This study used urine sample from 13 patients from Universiti Teknologi Malaysia (UTM) health centre for the urine analysis. Findings from the study revealed that six patients tested abnormal with mucus while only one patient tested abnormal with bacteria and two healthy. The test conducted from using Cyranose 320 shows that volatile compounds were present in their urine. Principal component analysis (PCA) was used to extract first and second principal components from 32 sensors used for the urine analysis. The study suggests the possibility of using e-nose as an early detection system for illness such as diabetes and bacterial infections.
目前的臨床診斷是基于生化、物理和微生物學方法。電子鼻系統用于檢測尿液樣本中的化學成分或揮發性有機化合物,是為了對不同的尿液成分進行分類,以便能夠準確診斷疾病和其他元素。本研究使用來自馬來西亞大學(UTM)健康中心的13名患者的尿液樣本進行尿液分析。研究結果顯示,6名患者出現粘液異常,只有1名患者出現細菌異常,2名患者健康。使用Cyranose 320電子鼻進行的試驗表明,尿液中存在揮發性化合物。主成分分析(PCA)用于從32個尿液分析傳感器中提取和第二主成分。研究表明,利用電子鼻作為糖尿病和細菌感染等疾病的早期檢測系統的可能性。