使用電子鼻診斷消化系統(tǒng)和呼吸系統(tǒng)疾病
Use of Electronic Noses for Diagnosis of Digestive and Respiratory Diseases through the Breath
Carlos Sánchez 1,2,J. Pedro Santos 1 andJesús Lozano 3,*
1Institute of Physics Technology and Information (CSIC),Madrid, Spain
2Up Devices and Technologies,Madrid, Spain
3Industrial Engineering School, University of Extremadura, 06006 Badajoz, Spain
*Author to whom correspondence should be addressed.
Biosensors 2019, 9(1), 35; https://doi.org/10.3390/bios9010035
Received: 12 January 2019 / Revised: 18 February 2019 / Accepted: 21 February 2019 / Published: 28 February 2019
Abstract
The increased occurrence of chronic diseases related to lifestyle or environmental conditions may have a detrimental effect on long-term health if not diagnosed and controlled in time. For this reason, it is important to develop new noninvasive early diagnosis equipment that allows improvement of the current diagnostic methods. This, in turn, has led to an exponential development of technology applied to the medical sector, such as the electronic nose. In addition, the appearance of this type of technology has allowed the possibility of studying diseases from another point of view, such as through breath analysis. This paper presents a bibliographic review of past and recent studies, selecting those investigations in which a patient population was studied with electronic nose technology, in order to identify potential applications of this technology in the detection of respiratory and digestive diseases through the analysis of volatile organic compounds present in the breath.
如果不及時診斷和控制，與生活方式或環(huán)境條件有關(guān)的慢性病的發(fā)病率增加可能對長期健康產(chǎn)生不利影響。因此，開發(fā)新的無創(chuàng)早期診斷設(shè)備，改進(jìn)現(xiàn)有的診斷方法是非常重要的。這反過來又導(dǎo)致了應(yīng)用于醫(yī)療領(lǐng)域的技術(shù)的指數(shù)級發(fā)展，如電子鼻。此外，這種技術(shù)的出現(xiàn)也使得從另一個角度研究疾病的可能性成為可能，比如通過呼吸分析。本文對過去和近的研究進(jìn)行了文獻(xiàn)綜述，選擇了使用電子鼻技術(shù)對患者群體進(jìn)行研究的研究對象，以確定該技術(shù)在呼吸和消化系統(tǒng)疾病檢測中的潛在應(yīng)用。呼吸中揮發(fā)性有機(jī)化合物的分析。
Keywords:electronic nose; gas sensors; biomarkers; diseases; digestive system; respiratory system; volatile organic compounds; breath
關(guān)鍵詞：電子鼻；氣體傳感器；生物標(biāo)志物；疾病；消化系統(tǒng)；呼吸系統(tǒng)；揮發(fā)性有機(jī)化合物；呼吸
