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組織損毀儀

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損毀儀于神經化學和神經藥理學研究。恒定的電流能夠確保測量結果有良好的重復性和由藥物對大腦皮層或大腦皮下層區域引起電休克進行精確測定。持續的電流等級通過反饋電路形成該電路還可調節動物間不同的阻抗。動物阻抗能夠被預測試和顯示并且在阻抗太高而不能發出理想的電流信號時會自動警報提示。


角膜和耳使用標準的電極也可根據實驗人員的需要定制電極。有逆變器、雙相單元、雙極型逆變器可選。

 

主要技術參數


Current Range 10 µA to 99 mA
Max Electrode Resistance 20 MO (10 µA) down to 2KO (100 mA)
Pulse Duration 1-99 sec. or manually controlled
Compliance Volatage 200V
Shipping Wt.: 6 lbs. (2.8 kg)
Dimensions (cm): 25 x 15 x 11

 

可根據需要選擇電休克儀


電休克儀


Electroconvulsive Device is designed for inducing convulsions in research animals. Consistent reproducible current levels are produced by feedback circuitry that adjust for variance in impedance of the contact from animal to animal.


主要技術參數


Frequency 1-299 pulses/sec.
Shock Duration 0.1-9.9 sec.
Compliance Voltage 2.5 kV
Current Range 1-99mA
Output Impedance 0 Ohm to 25 kOhm
Pulse Width 0.1 - 0.9 ms.
Pulse Rise and Fall Time 20 µs
LED Display 0 to 199 kOhm



相關引用文獻



S.M. Fortin et alia“Sampling Phasic Dopamine Signaling with Fast-Scan Cyclic Voltammetry in Awake, Behaving Rats” Current Protocols in Neuroscience, UNIT 7.25, published online 5 Jan 2015

§        V.D. Campese et alia“Lesions of lateral or central amygdala abolish aversive Pavlovian-to-instrumental transfer in rats” front Behav Neurosci. 8161, 2014

§        M.G. McCue et alia“Medial Amygdala Lesions Selectively Block Aversive Pavlovian–Instrumental Transfer in Rats” front Behav Neurosci. 8329, 2014

§        Stroobants et alia“PIncreased gait variability in mice with small cerebellar cortex lesions and normal rotarod performance” Behav. Brain Res. 24132-37, 2013

§        L.B. Cruz et alia“Effect of the bone marrow cell transplantation on elevated plus-maze perfor­mance in hippocampal-injured mice” Behav. Brain Res. available online Apr. 2013

§        M.B. Gomes et alia“Glucose levels Observed in Daily Clinical Practice induce Endothelial Dy­sfunction in the Rabbit Macro- and Microcircula­tion” Fund. & Clin. Pharmacol. 18 (3), 2004

§        C. Hamani et alia“Bilateral Anterior Thalamic Nucleus Lesions and High-frequency Stimula­tion Are Protective against Pilocarpine-induced Seizures and Status EpilepticusNeurosurgery, 54 (1)191-197, 2004


 

    

    

    

         

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