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tlyon000402 37450動態足底觸覺儀

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  • 公司名稱 圖拉揚科技
  • 品牌
  • 型號 tlyon000402
  • 所在地
  • 廠商性質 其他
  • 更新時間 2020/12/25 22:20:26
  • 訪問次數 633

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記錄持續時間和爪縮回時的作用力。

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  • 產品名稱:37450動態足底觸覺儀
  • 訂貨號:tlyon000402
  • 品牌名稱:意大利Ugo
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37450 - 動態足底觸覺儀

動態足底觸覺儀是用以自動評估嚙齒類動物跖面的“觸覺感應”。它與電子觸覺測量(Electronic Von Frey )和足底觸覺測量(Plantar Von Frey )類似,不同之處在于它能記錄持續時間和爪縮回時的作用力。

可移動的觸覺刺激裝置放于實驗動物足底,可根據實驗人員需要設定力的大小和力增大的速度等。

觸覺測量套件( Von Frey )以每次增加直徑0.05mm的細絲增加施力,直到受試動物的爪抽搐。

動態足底觸覺計的新模式為:

一臺可移動的觸覺刺激裝置,配備刺激絲和可調整角度的鏡子;

實為一微電子處理單位,提供數字顯示、內部數據存儲、可用閃存導出數據、可外接打印機;

寬敞的實驗操作平臺;

模塊化的動物籠,可自由組合3-12個隔間。

特征

優點

儀器自動施力

施力速度、方向等保持一致性

操作人員只需按動開關

相比用Von Frey測試,本實驗時間短,且操作人員不會感到沉悶

力的大小和增加量可預置

更多參數符合實驗需要

規格:

開始:

軟鍵

可設力范圍:

0 - 50.0 g, 分辨率為0.5 g

可設力增加率:

1 - 50 s, 分辨率為1s

著力絲移動范圍;

12 mm

實驗時間:

液晶屏顯示,分辨率為0.1s

連接電腦:

DELTA 9-pin 連接線

電源:

規格:

動物罩子:

85-264 VAC - 50-60Hz - 20 W max

85 x 40 x 40 cm

3個,每個20x20x14(h) cm

凈重:

12.50 Kg.

毛重:

包裝規格:

約21.50 Kg

98x49x47cm

附件:

37000-145:

面板內嵌式熱敏打印機

57145:

37450-278

37100

微型熱敏打印機

外加刺激,穿孔平臺和動物保護罩

兩組Durham動物抓持器,針對面部疼痛實驗

參考文獻:

提及動態足底觸覺儀的文獻:

- R. Lu, A. Schmidtko: “Direct Intrathecal Drug Delivery in Mice for Detecting In Vivo Effects of cGMP on Pain Processing” Methods in Molecular Biology 1020: 215-221, 2013

- I.Q. Russe et alia: “Activation of the AMP-Activated Protein Kinase Reduces Inflammatory Nociception” Journal of Pain 2, 2013

- J. Btesh et alia: “Mapping the Binding Site of TRPV1 on AKAP79: Implications for Inflammatory Hyperalgesia” J. Neuroscience 33 (21): 9184-9193, 2013

- V. Brázda et alia: “Dynamic Response to Peripheral Nerve Injury Detected by In Situ Hybridization of IL-6 and its Receptor mRNAs in the Dorsal Root Ganglia is not Strictly Correlated With Signs of Neuropathic Pain” Molecular Pain 9(42), 2013

- V. Shunmugavel et alia: “Simvastatin Ameliorates Cauda Equina Compression Injury in a Rat Model of Lumbar Spinal Stenosis” J. Neuroimmune Pharmacology 8 (1): 274-286, 2013

- O. Coste et alia: “The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP-kinase signaling and formalin-specific receptors” Behavioural Brain Research 234 (1): 121-128, 2012

- M.K. Boettger et alia: “Differential Effects of Locally and Systemically Administered Soluble Glycoprotein 130 on Pain and Inflammation in Experimental Arthritis” Arthritis Research & Therapy 12 (R140): 1-9, 2010

- A.L.M. Scott and M.S. Ramer: ” Schwann Cell p75NTR Prevents Spontaneous Sensory Reinnervation of the Adult Spinal Cord” Brain: 1-12, 2010

- M. Rosemann et alia: “Microphthalmia, Parkinsonism, and Enhanced Nociception in Pitx3416insG Mice” Mamm Genome 21: 12-27, 2010- D. Piomelli et alia:” Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism”.Nature NSC, 2010

- L. Ramer et alia: "Rho-Kinase Inhibition Enhances Axonal plasticity and Attenuates Cold Hyperalgesia after Dorsal Rhizotomy" J. Neuroscience, 24 (48), 10796-10805, 2004

- E. Escribano et alia: "Rapid Human Skin Permeation and Topical Anaesthetic Activity of a New Amethocaine Microemulsion" Skin Pharmacol. Physiol., 18, 294-300, 2004

- G. Villetti et alia: "Antinociceptive Activity of the N-Methyl-D-aspartate Receptor Antagonist N-(2-Indanyl)-glycinamide Hydrochloride (CHF3381) in Experimental Models of Inflammatory and Neuropathic Pain" J. Pharmacol. Exper. Therap., 306, 804-814, 2003
- M. Isabel Arévalo et alia: "Thermal Hyperalgesia and Light Touch Allodynia After Intradermal Mycobacterium butyricum Administration in Rat" Inflammation, 27 (5), 293-299, 2003
Durham Holders for Orofacial Stimulation
- F.G. Garrett, P.L. Durham et alia: “Validation of a Novel Rat-Holding Device for studying heat- and mechanical-Evoked Trigemi­nal Nocifensive Behavioral Responses” J. Orofacial Pain, 26 (4): 336- 344,2012
- F.G. Garrett, P.L. Durham et alia: “Development of a novel device for measuring withdrawal latency by thermal stimulation in rodent facial pain models using the Hargreaves Plantar Apparatus” Poster presented at SFN 2010


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